Publications

[Chps], [1997], [1998], [1999], [2000], [2001]

[2002], [2003], [2004], [2005], [2006], [2007]

[2008], [2009], [2010], [2011], [2012], [2013]

[2014], [2015], [2016], [2017], [2018], [2019],

[2020], [2021], [2022]

Publications 2022

F. Servin, J. A. Collins, J. S. Heiselman, K. C. Frederick-Dyer, V. B. Planz, S. K. Geevarghese, D. B. Brown, and M. I. Miga, "Fat quantification imaging and biophysical modeling for patient-specific forecasting of microwave ablation therapy", Frontiers in Physiology, Vol. 12, Article 820251, February 3, 2022 [PDF].

G. Lorenzo, J.S. Heiselman, M.A. Liss, M.I. Miga, H. Gomez, T.E. Yankeelov, T.J.R. Hughes, A. Reali. Patient-specific forecasting of prostate cancer growth during active surveillance using an imaging-informed mechanistic model. AACR Annual Meeting 2022, New Orleans, LA, USA, April 8-13, 2022 [PDF].

 G. Lorenzo, J.S. Heiselman, M.A. Liss, M.I. Miga, H. Gomez, T.E. Yankeelov, T.J.R. Hughes, A. Reali. Personalized computational forecasting of prostate cancer growth during active surveillance. 8th European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2022), Oslo, Norway, June 5-9, 2022 [PDF].

J. S. Heiselman, W. R. Jarnagin, and M. I. Miga, "Registration uncertainty in deforming organs: a novel approach for ensuring navigational confidence during image-guided procedures ", Proc. of SPIE Medical Imaging 2022: Image-guided Procedures, Robotic Interventions, and Modeling, 2022 [PDF].

B. Jacobson, A. K. Ding, M. Luo, K. Pereira, and M. I. Miga, "Controllability of the vagus nerve using directed electrode stimulation", Proc. of SPIE Medical Imaging 2022: Image-guided Procedures, Robotic Interventions, and Modeling, 2022 [PDF].

M. J. Ringel, W. L. Richey, J. S. Heiselman, M. Luo, I. M. Meszoely, and M. I. Miga, "Breast image registration for surgery: insights on material mechanics modeling ", Proc. of SPIE Medical Imaging 2022: Image-guided Procedures, Robotic Interventions, and Modeling, 2022 [PDF].

K. Hari, R. C. Vijayan, M. Luo, J. Tierney, J. S. Heiselman, L. B. Chambless, R. C. Thompson, and M. I. Miga, "Android application to display brain shift simulation in tumor resection procedures ", Proc. of SPIE Medical Imaging 2022: Image-guided Procedures, Robotic Interventions, and Modeling, 2022 [PDF].

W. L. Richey, J. S. Heiselman, M. J. Ringel, I. M. Meszoely, and M. I. Miga, "Tumor deformation correction for an image guidance system in breast conserving surgery", Proc. of SPIE Medical Imaging 2022: Image-guided Procedures, Robotic Interventions, and Modeling, 2022 [PDF].

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Publications 2021

W. L. Richey, J. S. Heiselman, M. Luo, I. M. Meszoely, and M. I. Miga, "Impact of deformation on a supine-positioned image-guided breast surgery approach", International Journal of Computer Assisted Radiology and Surgery, Vol. 16, No. 11, pp. 2055-2066, 2021 [PDF].

M. I. Miga and R. F. Labadie, "A novel clinically immersive pre-doctoral training program for engineering in surgery and intervention: Initial realization and preliminary results", Biomedical Engineering Education, June 7, 2021 [PDF].

M.Luo, S. Narasimhan, P. S. Larson, A. J. Martin, P. E. Konrad, and M. I. Miga, "Impact of brain shift on neural pathways in deep brain stimulation: a preliminary analysis via multi-physics finite element models", Journal of Neural Engineering, Vol. 18, No. 5, 2021 [PDF].

A. E. Dohm, T. M. Nickles, C. E. Miller, H. J. Bowers, M. I. Miga, A. Attia, and M. D. Chan, and J. A. Weis, "Clinical assessment of a biophysical model for distinguishing tumor progression from radiation necrosis", Medical Physics, (accepted), 2021 [PDF].

J. S. Heiselman, and M. I. Miga, "Strain Energy Decay Predicts Elastic Registration Accuracy from Intraoperative Data Constraints", IEEE Transactions on Medical Imaging, (accepted), 2021 [PDF].

P. Alvarez, S. Rouze, M. I. Miga, Y. Payan, J. Dillenseger, and M. Chabanas, "A hybrid, image-based and biomechanics-based registration approach to markerless intraoperative nodule localization during video-assisted thoracoscopic surgery", Medical Image Analysis, (accepted), 2021 [PDF].

A. Ding, M. Luo, and M. I. Miga, "Modeling the effects of bipolar helical cuff electrodes in vagus nerve stimulation", Proc. of SPIE Medical Imaging 2021: Image-guided Procedures, Robotic Interventions, and Modeling, 2021 [PDF].

J. S. Heiselman, W. L. Richey, S. Taylor, and M. I. Miga, "Improving accuracy of image-to-physical laparoscopic liver registration via reconstruction of intrahepatic pressure changes from abdominal insufflation", Proc. of SPIE Medical Imaging 2021: Image-guided Procedures, Robotic Interventions, and Modeling, 2021 [PDF].

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Publications 2020

J. S. Heiselman, W. R. Jarnagin, and M. I. Miga, "Intraoperative correction of liver deformation using sparse surface and vascular features via linearized iterative boundary reconstruction", IEEE Transactions on Medical Imaging, Vol. 39, No. 6, pp. 2223-2234, 2020 [PDF].         

J. A. Collins, J. S. Heiselman, L. W. Clements, J. A. Weis, D. B. Brown, and M. I. Miga, "Toward Image Data-Driven Predictive Modeling for Guiding Thermal Ablative Therapy", IEEE Transactions on Biomedical Engineering, Vol. 67, No. 6, pp. 1548-1557, 2020 [PDF].

M. Luo, P. S. Larson, A. J. Martin, and M. I. Miga, "Accounting for Deformation in Deep Brain Stimulation Surgery with Models:  Comparison to Interventional Magnetic Resonance Imaging biomechanical", IEEE Transactions on Biomedical Engineering, Vol. 67, No. 10, pp. 2934-2944, 2020 [PDF].

S. Narasimhan, J. A. Weis, M. Luo, A. L. Simpson, R. C. Thompson, and M. I. Miga, "Accounting for intraoperative brain shift ascribable to cavity collapse during intracranial tumor resection," Journal of medical imaging (Bellingham, Wash.), vol. 7, no. 3, pp. 031506-031506, 2020-May [PDF].

S. Frisken, M. Luo, J. Parikshit, A. Bunevicius, I. Machado, P. Unadkat, M. Bertotti, M. Toews, W. M. Wells, M. I. Miga, and A. J. Golby, "A comparison of thin-plate spline deformation and finite element modeling to compensate for brain shift during tumor resection", International Journal of Computer Assisted Radiology and Surgery, Vol. 15, pp. 75-84, 2020 [PDF].

H. Bow, X. Yang, S. Chotai, M. Feldman, H. Yu, D. Englot, M. Miga, S. Pruthi, B. Dawant, and S. L. Parker, "Initial experience with using a structured light 3D scanner and image registration to plan bedside Subdural Evacuating Port System placement," World Neurosurg, Feb 4 2020 [PDF].

A. L. Simpson and M. I. Miga, "Special Section Guest Editorial: Interventional and Surgical Data Science for Data-Driven Patient Outcomes," Journal of Medical Imaging, vol. 7, no. 3, p. 031501, 2020. [PDF].

W. Richey, J. Heiselman, M. Luo, I. Meszoely, and M. I. Miga, Textual fiducial detection in breast conserving surgery for a near-real time image guidance system (SPIE Medical Imaging). SPIE, 2020. [PDF].

A. Ding, J. Heiselman, and M. I. Miga, Image data-driven thermal dose prediction for microwave ablation therapy (SPIE Medical Imaging). SPIE, 2020. [PDF].

J. Heiselman and M. I. Miga, The image-to-physical liver registration sparse data challenge: characterizing inverse biomechanical model resolution (SPIE Medical Imaging). SPIE, 2020. [PDF].

J. Heiselman, W. R. Jarnagin, and M. I. Miga, Deformable registration of the liver using sparse intraoperative data: Incorporating hepatic feature constraints fromt tracked intraoperative ultrasound Proceedings of Computer-Aided and Robotic Surgery (CARS), 2020. [PDF].

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Publications 2019

X. Yang, S. Narasimhan, M. Luo, R. C. Thompson, L. B. Chambless, P. J. Morone, L. He, B. M. Dawant, and M. I. Miga, "Development and evaluation of a trackerless surgical planning and guidance system based on 3D Slicer", Journal of Medical Imaging, Vol. 6, No. 3, pp. 035002-1-12, 2019 [PDF].

M. Luo, P. S. Larson, A. J. Martin, P. Konrad, and M. I. Miga, "An Integrated Multi-Physics Finite Element Modeling Framework for Deep Brain Stimulation: Preliminary Study on Impact of Brain Shift on Neuronal Pathways", Lecture Notes in Computer Science, (accepted), 2019 [PDF].

M. I. Miga, J. A. Collins, J. S. Heiselman, and D. B. Brown "Toward a patient-specific image data-driven predictive modeling framework for guiding microwave ablative therapy", Lecture Notes in Computational Vision and Biomechanics, (accepted), 2019  [PDF].

J. A. Collins, J. S. Heiselman, L. W. Clements, D. B. Brown, and M. I. Miga, 'Multiphysics modeling toward enhanced guidance in hepatic microwave ablation: a preliminary framework', Journal of Medical Imaging, Vol. 6, No. 2, pp. 025007, 2019 [PDF].

A. E. Dohm, T. Nickles, H. Johnson, M. I. Miga, A. Attia, M. D. Chan, J. A. Weis, 'Imaging-driven Biophysical Model for the Differentiation of Tumor Progression from Radiation Necrosis', International Journal of Radiation Oncology Biology Physics, Meeting Abstract vol. 105, no. 1, pp. S31-S31, Sep 2019 [PDF].

J. Siewerdsen, K. Cleary, M. I. Miga, J. Paydarfar, "Advances in image-guided interventions," Medical Physics, Vol. 46, No. 6, pp. E460, 2019.

S. Narasimhan, H. B. Johnson, T. M. Nickles, M. I. Miga, N. Rana, A. Attia, et al., "Biophysical model-based parameters to classify tumor recurrence from radiation-induced necrosis for brain metastases," Medical physics, 2019-Feb-28 2019 [PDF].

L. M. Pak, J. Gagniere, P. J. Allen, V. P. Balachandran, M. I. D'Angelica, R. P. DeMatteo, et al., "Utility of Image Guidance in the Localization of Disappearing Colorectal Liver Metastases," Journal of Gastrointestinal Surgery, vol. 23, pp. 760-767, Apr 2019 [PDF].

M. I. Miga, J. A. Collins, J. S. Heiselman, and D. B. Brown, 'Toward a Patient-Specific Image Data-Driven Predictive Modeling Framework for Guiding Microwave Ablative Therapy,' Proceedings of 16th International Symposium on Computer Methods in Biomechanics and Biomedical Engineering, 2019. [PDF]

M. I. Miga, 'Engineering in Surgery and Intervention:  A Novel Program in Clinical Immersion for Procedural Medicine', Proceedings of 2019 BMES Annual Meeting, 10/16-10/19, Philadelphia PA, 2019. [PDF].

P. Alvarez, S. Narasimhan, S. Rouze, J. Dillenseger, Y. Payan, M. I. Miga, M. Chabanas, 'Biphasic Model of Lung Deformations for Video-assisted Thoracoscopic Surgery (VATS),' Proceedings of IEEE International Symposium on Biomedical Imaging, 2019. [PDF].

S. Frisken, M. Luo, I. Machado, P. Unadkat, P. Juvekar, A. Bunevicius, M. Toews, J. Luo, W. M. Wells M. I. Miga, and A. J. Golby, 'Preliminary Results Comparing Thin Plate Splines with Finite Element Methods for Modeling Brian Deformation during Neurosurgery Using Intraoperative Ultrasound', Proc. of SPIE Medical Imaging 2019: Image-Guided Procedures, Robotic Interventions, and Modeling Conference, 2019. [PDF].

E. L. Brewer, L. W. Clements, J. A. Collins, D. J. Doss, J. S. Heiselman, M. I. Miga, C. D.Pavas, and E. H. Wisdom III, 'The Image-to-Physical Liver Registration Sparse Data Challenge', Proc. of SPIE Medical Imaging 2019: Image-Guided Procedures, Robotic Interventions, and Modeling Conference, 2019. [PDF].

D. J. Doss, J. S. Heiselman, M. Luo, L. W. Clements, M. I. Miga, D. Brown, and F. Banovac,'Quantitative Imaging Analysis to Guide Biopsy for Molecular Biomarkers',  Proc. of SPIE Medical Imaging 2019: Image-Guided Procedures, Robotic Interventions, and Modeling Conference, 2019. [PDF].

M. Luo, S. F. Frisken, S. Narasimhan, L. W. Clements, R. C. Thompson, A. J. Golby, and M. I. Miga,'A Comprehensive Model-Assisted Brain Shift Correction Approach in Image-Guided Neurosurgery: A Case Study in Brain Swelling and Subsequent Sag After Craniotomy',  Proc. of SPIE Medical Imaging 2019: Image-Guided Procedures, Robotic Interventions, and Modeling Conference, 2019. [PDF].

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Publications 2018

D. A. Hormuth, S. L. Eldridge, J. A. Weis, M. I. Miga, and T. E. Yankeelov, 'Mechanically Coupled Reaction-Diffusion Model to Predict Glioma Growth: Methodological Details,' in Cancer Systems Biology: Methods and Protocols. vol. 1711, L. VonStechow, Ed., ed, 2018, pp. 225-241. [PDF]

D. A. Hormuth, J. A. Weis, S. L. Barnes, M. I. Miga, V. Quaranta, and T. E. Yankeelov, 'Biophysical Modeling of In Vivo Glioma Response After Whole-Brain Radiation Therapy in a Murine Model of Brain Cancer,' International Journal of Radiation Oncology Biology Physics, vol. 100, pp. 1270-1279, Apr 2018. [PDF].

S. Narasimhan, J. A. Weis, H. F. J. Gonzalez, R. C. Thompson, and M. I. Miga, "In vivo modeling of interstitial pressure in a porcine model: approximation of poroelastic properties and effects of enhanced anatomical structure modeling," Journal of Medical Imaging, vol. 5, Oct 2018 [PDF].

A. Simpson and M. Miga, 'Technology Platforms for Treatment and Discovery in Human Systems: Novel Work in Image-Guided Procedures, Robotic Interventions, and Modeling,' Journal of Medical Imaging, vol. 5, Apr 2018. [PDF].

J. S. Heiselman, L. W. Clements, J. A. Collins, J. A. Weis, A. L. Simpson, S. K. Geevarghese, T. P. Kingham, W. R. Jarnagin, and M. I. Miga, 'Characterization and correction of intraoperative soft tissue deformation in image-guided laparoscopic liver surgery', Journal of Medical Imaging, vol. 5, Apr 2018. [PDF].

R. H. Griesenauer, J. A. Weis, L. R. Arlinghaus, I. M. Meszoely, and M. I. Miga, 'Toward quantitative quasistatic elastography with a gravity-induced deformation source for image-guided breast surgery', Journal of Medical Imaging, (accepted), 2018 [PDF].

S. Narasimhan, M. I. Miga, N. Rana, H. B. Johnson, A. Attia, J. A. Weis, et al., "DIFFERENTIATING TUMOR RECURRENCE FROM RADIATION-INDUCED NECROSIS: AN IMAGE-BASED MATHEMATICAL MODELING FRAMEWORK," in 2018 Ieee 15th International Symposium on Biomedical Imaging, ed, 2018, pp. 839-842 [PDF].

X. Yang, R. Vijayan, M. Luo, L. W. Clements, R. C. Thompson, B. M. Dawant, and M. I. Miga, 'Trackerless surgical image-guided system design using an interactive extension of 3D Slicer', SPIE Medical Imaging 2018: Image-Guided Procedures, Robotic Interventions, and Modeling Conference, (in press), 2018 [PDF].

M. Luo, S. Narasimhan, A. J. Martin, P. S. Larson, and M. I. Miga, 'Model-based correction for brain shift in deep brain stimulation burr hole procedures: a comparison using interventional magnetic resonance imaging', SPIE Medical Imaging 2018: Image-Guided Procedures, Robotic Interventions, and Modeling Conference, (in press), 2018 [PDF].

J. S. Heiselman, J. A. Collins, L. W. Clements, J. A. Weis, A. L. Simpson, S. K. Geevarghese, T. P. Kingham, W. R. Jarnagin, and M. I. Miga, 'Technical Note: Nonrigid registration of laparoscopic lier surgery using sparse intraoperative data', SPIE Medical Imaging 2018: Image-Guided Procedures, Robotic Interventions, and Modeling Conference, (in press), 2018 [PDF].

W. L. Richey, M. Luo, S. E. Goodale, L. W. Clements, I. M. Meszoely, and M. I. Miga, 'A system for automatic monitoring of surgical instruments and dynamic, non-rigid surface deformations in breast cancer surgery', SPIE Medical Imaging 2018: Image-Guided Procedures, Robotic Interventions, and Modeling Conference, (in press), 2018 [PDF].

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Publications 2017

L. W. Clements, J. A. Collins, J. A. Weis, A. L. Simpson, T. P. Kingham, W. R. Jarnagin, M. I. Miga, 'Deformation correction for image guided liver surgery: An intraoperative fidelity assessment', Surgery, Vol. 162, No. 3, pp. 537-547, 2017 [PDF].

M. Luo, S. F. Frisken, J. A. Weis, L. W. Clements, P. Unadkat, R. C. Thompson, A. J. Golby, and M. I. Miga, 'Retrospective study comparing model-based deformation correction to intraoperative magnetic resonance imaging for image-guided neurosurgery', Journal of Medical Imaging, Vol. 4, No. 3, DOI: 10.1117/1.JMI.4.3.035002, 2017 [PDF].

X. Yang, L. W. Clements, M. Luo, S. Narasimhan, R. C. Thompson, B. M. Dawant, and M. I. Miga, 'Stereovision-based integrated system for point cloud reconstruction and simulated brain shift validation', Journal of Medical Imaging, Vol. 4, No. 3, DOI: 10.1117/1.JMI.4.3.035002, 2017. [PDF]

R. H. Griesenauer, J. A. Weis, L. R. Arlinghaus, I. M. Meszoely, and M. I. Miga, 'Breast stiffness estimation for surgical guidance using gravity-induced excitation', Physics in Medicine and Biology, Vol. 62, No. 12, pp. 4756-4776, 2017 [PDF].

M. T. McKenna, J. A. Weis, S. L. Barnes, D. R. Tyson, M. I. Miga, V. Quaranta, T. E. Yankeelov, 'A predictive mathematical modeling approach for the study of doxorubicin treatment in triple negative breast cancer', Scientific Reports, Vol. 7, No. 5725, 2017 [PDF].

D. A. Hormuth, J. A. Weis, S. L. Barnes, M. I. Miga, E. C. Rericha, V. Quaranta, T. E. Yankeelov, 'A mechanically coupled reaction-diffusion model that incorporates intra-tumoural heterogeneity to predict in vivo glioma growth', Journal of the Royal Society Interface, Vol. 14, No. 128, DOI: 10.1098/rsif.2016.1010, 2017 [PDF].

J. A. Collins, J. A. Weis, J. S. Heiselman, L. W. Clements, A. L. Simpson, W. R. Jarnagin, and M. I. Miga, 'Improving registration robustness for image-guided liver surgery in a novel human-to-phantom data framework', IEEE Transactions on Medcial Imaging, Available Online, 2017 [PDF].

R. C. Vijayan, R. C. Thompson, L. B. Chambless, P. J. Morone, L. He, L. W. Clements, R. H. Griesenauer, H. Kang, and M. I. Miga, 'Android application for determining surgical variables in brain-tumor resection procedures', Journal of Medical Imaging, Vol. 4, No. 1, A#:015003, 2017 [PDF].

J. A. Weis, M. I. Miga, and T. E. Yankeelov, 'Three-dimensional image-based mechanical modeling for predicting the response of breast cancer to neoadjuvant therapy', Computer Methods in Applied Mechanics and Engineering, Vol.314, No. SI, pp. 494-512 [PDF].

J. A. Collins, J. S. Heiselman, J. A. Weis, L. W. Clements, A. L. Simpson, W. R. Jarnagin, and M. I. Miga, 'On the nature of data collection for soft-tissue image-to-physical organ registration: A noise characterization study', SPIE Medical Imaging: Image-guided Procedures, Robotic Interventions, and Modeling Conference, Vol. 10135, 2017 [PDF].

J. S. Heiselman, J. A. Collins, L. W. Clements, J. A. Weis, A. L. Simpson, S. K. Geevarghese, W. R. Jarnagin, and M. I. Miga, 'Emulation of the laparoscopic environment for image-guided liver surgery via an abdominal phantom system with anatomical ligamenture', SPIE Medical Imaging: Image-guided Procedures, Robotic Interventions, and Modeling Conference, Vol. 10135, 2017 [PDF].

S. Narasimhan, J. A. Weis, I. S. Godage, R. Webster, K. Weaver, and M. I. Miga, 'Development of a mechanics-based model of brain deformations during intracerebral hemorrhage evacuation', SPIE Medical Imaging: Image-guided Procedures, Robotic Interventions, and Modeling Conference, Vol. 10135, 2017 [PDF].

X. Yang, L. W. Clements, M. Luo, S. Narasimhan, R. C. Thompson, B. M. Dawant, and M. I. Miga, 'Integrated system for point cloud reconstruction and simulated brain shift validation using tracked surgical microscope', SPIE Medical Imaging: Image-guided Procedures, Robotic Interventions, and Modeling Conference, Vol. 10135, 2017 [PDF].

D. J. Doss, J. S. Heiselman, J. A. Collins, J. A. Weis, L. W. Clements, S. K. Geevarghese, and M. I. Miga, 'Using an android application to assess registration strategies in open hepatic procedures: A planning and simulation tool', SPIE Medical Imaging: Image-guided Procedures, Robotic Interventions, and Modeling Conference, Vol. 10135, 2017 [PDF].

R. H. Griesenauer, J. A. Weis, L. R. Arlinghaus, I. M. Meszoely, and M. I. Miga, 'Towards quantitative quasi-static elastography with a gravity-induced deformation source', SPIE Medical Imaging: Image-guided Procedures, Robotic Interventions, and Modeling Conference, Vol. 10135, 2017 [PDF].

M. Luo, S. F. Frisken, J. A. Weis, L. W. Clements, P. Unadkat, R. C. Thompson, A. J. Golby, and M. I. Miga, 'Validation of model-based brain shift correction in neurosurgery via intraoperative magnetic resonance imaging: Preliminary results', SPIE Medical Imaging: Image-guided Procedures, Robotic Interventions, and Modeling Conference, Vol. 10135, 2017 [PDF].

W. R. Jarnagin, A. L. Simpson, and M. I. Miga, 'Towards integrated image guided liver surgery', SPIE Medical Imaging: Image-guided Procedures, Robotic Interventions, and Modeling Conference, Vol. 10135, 2017 [PDF].

B. Ma, T. P. Kingham, M. I. Miga, W. R. Jarnagin, A. L. Simpson, 'Liver segmentation in color images', SPIE Medical Imaging: Image-guided Procedures, Robotic Interventions, and Modeling Conference, Vol. 10135, 2017 [PDF].

M. T. McKenna, S. L. Barnes, J. A. Weis, A. M. Searfoss, D. R. Tyson, E. C. Rericha, M. I. Miga, V. Quaranta, and T. E. Yankeelov, 'Predicting the response of triple negative breast cancer to doxorubicin', Cancer Research, Vol. 77, No. 2, A14, 2017.

D. A. Hormuth, J. A. Weis, S. B. Eldridge, M. I. Miga, E. C. Rericha, V. Quaranta, and T. E. Yankeelov, 'Predicting response to the whole brain radiotherapy in a murine model of glioma', Cancer Research, Vol. 77, No. 2, A09, 2017.

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Publications 2016

M. I. Miga, 'Computational modeling for enhancing soft tissue image guided surgery: An application in neurosurgery', Annals of Biomedical Engineering, Vol. 44, No. 1, pp. 128-138, 2016 [PDF].

T. E. Yankeelov, and M. I. Miga, , 'Introduction to the Special Section on Clinical Applications of Multi-Scale Modeling', Annals of Biomedical Engineering, Vol. 44, No. 9, pp. 2589-2590, 2016 [PDF].

G. S. Kassab, G. An, E. A. Sander, M. I. Miga, J. M. Guccione, S. Ji, and Y. Vodovotz, 'Augmenting surgery via multi-scale modeling and translational systems biology in the era of precision medicine: A multidisciplinary perspective', Annals of Biomedical Engineering, DOI: 10.1007/s10439-016-1596-4, 2016 [PDF].

L. W. Clements, J. A. Collins, J. A. Weis, A. L. Simpson, L. B. Adams, W. R. Jarnagin, and M. I. Miga, 'Evaluation of model-based deformation correction in image-guided liver surgery via tracked intraoperative ultrasound', Journal of Medical Imaging, Vol. 3, No. 1, 2016 [PDF].

M. I. Miga, K. Sun, I. Chen, L. W. Clements, T. S. Pheiffer, A. L. Simpson, R. C. Thompson 'Clinical evaluation of a model-updated image-guidance approach to brain shift compensation: experience in 16 cases', International Journal for Computer Assisted Radiology and Surgery, Vol. 11, No. 8, pp. 1467-1474, 2016 [PDF].

R. E. Ong, C. L. Glisson, J. Burgner-Kahrs, A. L. Simpson, A. Danilchenko, R. Lathrop, S. D. Herrell, R. J. Webster, M. I. Miga, and R. L. Galloway, 'A novel method for texture-mapping conoscopic surfaces for minimally invasive image-guided kidney surgery', International Journal of Computer Assisted Radiology and Surgery, Vol. 11, No. 8, pp. 1515-1526, 2016 [PDF].

J. T. Chadwell, R. H. Conley, J. A. Collins, I. M. Meszoely, and M. I. Miga, 'Characterization of a phantom setup for breast conserving cancer surgery', SPIE 2016 Medical Imaging: Image-Guided Procedures, Robotic Interventions, Vol. 9786, 2016 [PDF].  

R. Vijayan, R. H. Conley, R. C. Thompson, L. W. Clements, and M. I. Miga, 'Determination of surgical variables for a brain shift correction pipeline using an android application', SPIE 2016 Medical Imaging: Image-Guided Procedures, Robotic Interventions, Vol. 9786, 2016 [PDF].  

X. Yang, L. W. Clements, R. H. Conley, R. C. Thompson, B. M. Dawant, and M. I. Miga, 'A novel cranitomy simulation system for evluation of stereo-pair reconstruction fidelity and tracking', SPIE 2016 Medical Imaging: Image-Guided Procedures, Robotic Interventions, Vol. 9786, 2016 [PDF].  

 N. Rana, J. A. Weis, M. I. Miga, R. C. Thompson, K. D. Weaver, L. B. Chambless, A. J. Cmelak, and A. Attia, 'Image-based mathematical modeling to differentiate radiation-induced necrosis from tumor recurrence following stereotactic radiosurgery for intracranial metastasis',  International Journal of Radiation Oncology Biology Physics, Vol. 96, No. 2, E703, 2016 [PDF].

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Publications 2015

J. A. Weis, K. M. Flint, V. Sanchez, T. E. Yankeelov, and M. I. Miga, 'Assessing the accuracy and reproducibility of modality independent elastography in a murine model of breast cancer', Journal of Medical Imaging, Vol. 2, No. 3, 036001-1-11, 2015 [PDF].

J. A. Weis, M. I. Miga, L. R. Arlinghas, X. Li, V. Abramson, A. B. Chakrvarthy, P. Pendyala, and T. E. Yankeelov, 'Predicting the response of breast cancer to neoadjuvant therapy using a mechanically coupled reaction-diffusion equation', Cancer Research, Vol. 75, No. 22, pp. 4697-4707, 2015 [PDF].

T. S. Pheiffer, and M. I. Miga, 'Toward a generic real-time compression correction framework for tracked ultrasound', International Journal for Computer Assisted Radiology and Surgery, DOI 10.1007/s11548-015-1210-5, 2015 [PDF].

R. H. Conley, I. M. Meszoely, J. A. Weis, T. S. Pheiffer, L. R. Arlinghaus, T. E. Yankeelov, and M. I. Miga, 'Realization of a biomechanical model-assisted image guidance system for breast cancer surgery using supine MRI', International Journal of Computer Assisted Radiology and Surgery, DOI 10.1007/s11548-015-1235-9, 2015 [PDF].

D. A. Hormuth, J. A. Weis, S. L. Barnes, M. I. Miga, E. C. Rericha, V. Quaranta, and T. E. Yankeelov, 'Predicting in vivo glioma growth with the reaction diffusion equation constrained by quantitative magnetic resonance imaging data', Physical Biology, Vol. 12, 2015 [PDF].

A. N. Kumar, M. I. Miga, T. S. Pheiffer, L. B. Chambless, R. C. Thompson, and B. M. Dawant, 'Persistent and automatic intraoperative 3D digitization of surfaces under dynamic magnifications of an operating microscope', Medical Image Analysis, Vol. 19, pp. 30-45, 2015 [PDF].

A. L. Simpson, J. N. Leal, A. Pugalenthi, P. J. Allen, R. P. DeMatteo, Y. Fong, M. Gonen, W.  R. Jarnagin, T. P. Kingham, M. I. Miga, J. Shia, M. R. Weiser, and M. I D'Angelica, 'Chemotherapy-Induced Splenic Volume Increase Is Independently Associated with Major Complications after Hepatic Resection for Metastatic Colorectal Cancer', Journal of the American College of Surgeons, vol. 220, No.3, pp. 271-280, March, 2015 [PDF]

A. L. Simpson, L. B. Adams, P. J. Allen, M. I D'Angelica, R. P. DeMatteo, Y. Fong, P. Kingham, U. Leung, M. I. Miga, E. P. Parada, W. R. Jarnagin, R. K. Do,  'Texture analysis of preoperative CT images for prediction of postoperative hepatic insufficiency: A preliminary study', Journal of the American College of Surgeons, vol. 220, No.3, pp. 339-346, March, 2015 [PDF]

D. A. Hormuth, J. A. Weis, M. I. Miga, and T. E. Yankeelov, 'A mechanically coupled reaction-diffusion model for predicting in vivo C6 glioma growth in rats', Cancer Research, Vol. 75, Supplement 23, Abstract A42, 2015.

J. A. Collins, D. B. Brown, T. P. Kingham, W. R. Jarnagin, M. I. Miga, and L. W. Clements, "Method for evaluation of predictive models of microwave ablation via post-procedural clinical imaging", SPIE 2015 Medical Imaging: Image-Guided Procedures, Robotic Interventions, (in press), Orlando, FL, 2015 [PDF].  

L. W. Clements, J. A. Collins, A. L. Simpson, Y. Wu, W. R. Jarnagin, and M. I. Miga, "Validation of model-based deformation correction in image-guided liver surgery via tracked intraoperative ultrasound: preliminary method and results", SPIE 2015 Medical Imaging: Image-Guided Procedures, Robotic Interventions, (in press), Orlando, FL, 2015 [PDF].  

J. A. Weis, A. M. Johnsen, G. E. Wile, T. E. Yankeelov, R. G. Abramson, and M. I. Miga, "Development of a diaphragmatic motion-based elastography framework for assessment of liver stiffness", SPIE 2015 Medical Imaging: Biomedical Applications in Molecular, Structural, and Functional Imaging, (in press), Orlando, FL, 2015 [PDF].  

K. M. Flint, J. A. Weis, T. E. Yankeelov, and M. I. Miga, "Repeatability assessment of modality independent elastography in a pre-clinical murine model", SPIE 2015 Medical Imaging: Biomedical Applications in Molecular, Structural, and Functional Imaging, (in press), Orlando, FL, 2015 [PDF].  

U. Leung, A. L. Simpson, L. B. Adams, W. R. Jarnagin, M. I. Miga, and T. P. Kingham, "Image guidance improves localization of sonographically occult colorectal liver metastases", SPIE 2015 Medical Imaging: Image-Guided Procedures, Robotic Interventions, (in press), Orlando, FL, 2015 [PDF].

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Publications 2014

U. Leung, A. L. Simpson, R. L. C. Araujo, M. Goenen, C. McAuliffe, M. I. Miga, et al., "Remnant Growth Rate after Portal Vein Embolization Is a Good Early Predictor of Post-Hepatectomy Liver Failure," Journal of the American College of Surgeons, vol. 219, pp. 620-630, Oct 2014 [PDF].

A. L. Simpson, D. A. Geller, A. W. Hemming, W. R. Jarnagin, L. W. Clements, M. I. D'Angelica, P. Dumpuri, M. Gonen, I. Zendejas, M. I. Miga, and J. D. Stefansic, "Liver planning software accurately predicts postoperative liver volume and measures early regeneration", Journal of the American College of Surgeons, Vol. 219, Issue 2, pp. 199-207, 2014 [PDF].

K. Sun, T. S. Pheiffer, A. L. Simpson, R. C. Thompson, and M. I. Miga,  "Near real-time computer assisted surgery for brain shift correction using biomechanical models", IEEE Journal of Translational Engineering in Health and Medicine, Vol. 2, pp. 2500113, 2014 [PDF].

A. L. Simpson, K. Sun, T. S. Pheiffer, D. C. Rucker, A. K. Sills, R. C. Thompson, and  M. I. Miga,  "Evaluation of conoscopic holography for estimating tumor resection cavities in model-based image-guided neurosurgery", IEEE Transactions on Biomedical Engineering, Vol. 61, Issue 6, pp. 1833-1843, 2014 [PDF].

T. S. Pheiffer, R. C. Thompson, D. C. Rucker, A. L. Simpson, and M. I. Miga,  "Model-based correction of tissue compression for tracked ultrasound in soft tissue image-guided surgery", Ultrasound in Medicine and Biology, Vol. 40, Issue 4, pp. 788-803, 2014 [PDF].

D. C. Rucker, Y. Wu, L. W. Clements, J. E. Ondrake, T. S. Pheiffer, A. L. Simpson, W. R. Jarnagin, and M. I. Miga,  "A mechanics-based nonrigid registration method for liver surgery using sparse intraoperative data", IEEE Transactions on Medical Imaging, Vol. 33, Issue 1, pp. 147-158, 2014 [PDF].

A. L. Simpson, R. K. Do, E. P. Parada, M. I. Miga, and W. R. Jarnagin,  "Texture feature analysis for prediction of postoperative liver failure prior to surgery", SPIE 2014 Medical Imaging: Image Processing Conference, Vol. 9034, San Diego, CA, April 2014 [PDF].

D. K. Kim, J. A. Weis, T. E. Yankeelov, and M. I. Miga,  "Utilizing a reference material for assessing absolute tumor mechanical properties in modality independent elastography", SPIE 2014 Medical Imaging: Biomedical Applications in Molecular, Structural, and Functional Imaging Conference, Vol. 9038, San Diego, CA, April 2014 [PDF].

J. A. Weis, D. K. Kim, T. E. Yankeelov, and M. I. Miga,  "Validating and reproducibility assessment of modality independent elastography in a pre-clinical model of breast cancer", SPIE 2014 Medical Imaging: Biomedical Applications in Molecular, Structural, and Functional Imaging Conference, Vol. 9038, San Diego, CA, April 2014 [PDF].

Y. Wu, D. C. Rucker, R. H. Conley, T. S. Pheiffer, A. L. Simpson, S. K. Geevarghese, and M. I. Miga, 'Registration of liver images to minimally invasive intraoperative surface and subsurface data', SPIE 2014 Medical Imaging: Image-guided Procedures, Robotic Interventions, and Modeling Conference, Vol. 9036, San Diego, CA, April 2014 [PDF].

R. H. Conley, I. M. Meszoely, T. S. Pheiffer, J. A. Weis, T. E. Yankeelov, and M. I. Miga, 'Image to physical space registration of supine breast MRI for image guided breast surgery', SPIE 2014 Medical Imaging: Image-guided Procedures, Robotic Interventions, and Modeling Conference, Vol. 9036, San Diego, CA, April 2014 [PDF].

L. W. Clements, I.  Norton, A. J. Golby, R. C. Thompson, W. E. Wells, and M. I. Miga, 'Towards validation of a model-based deformation correction approach in image-guided neurosurgery via intraoperative magnetic resonance imaging', Proc. of 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Chicago, IL, August 2014 [PDF].

A. N. Kumar, M. I. Miga, T. S. Pheiffer, L. B. Chambless, R. C. Thompson, and B. M. Dawant, 'Automatic tracking of intraoperative brain surface displacements in brain tumor surgery', Proc. of 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Chicago, IL, August 2014 [PDF].

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Publications 2013

T. E. Yankeelov, N. Atuegwu, D. Hormuth, J. A. Weis, S. L. Barnes, M. I. Miga, E. C. Rericha, V. Quaranta ,  "Clinically relevant modeling of tumor growth and treatment response", Science Translational Medicine, Vol. 5, Issue 187, pp. 1-5,  2013 [PDF].

J. A. Weis, M. I. Miga, L. R. Arlinghaus, X. Li, A. B. Chakravarthy, V. Abramson, J. Farley, and T. E. Yankeelov,  "A mechanically coupled reaction-diffusion model for predicting the response of breast tumors to neoadjuvant chemotherapy", Physics in Medicine and Biology, Vol. 58, pp. 5851-5866,  2013 [PDF].

D. C. Rucker, J. Das, H. B. Gilbert, P. J. Swaney, M. I. Miga, N. Sarkar, R. J. Webster, "Sliding mode control for steerable needles", Vol. 29, Issue 5, pp. 1289-1299, 2013 [PDF].

I. Chen, R. E. Ong, A. L. Simpson, K. Sun, R. C. Thompson, and M. I. Miga,  "Integrating retraction modeling into an atlas-based framework for brain shift correction", IEEE Transactions on Biomedical Engineering, Vol. 60, Issue 12, pp. 3494-3504,  2013 [PDF].

A. L. Simpson, P. Dumpuri, J. E. Ondrake, J. A. Weis, W. R. Jarnagin, and M. I. Miga,  "Preliminary study of a novel method for conveying corrected image volumes in surgical navigation", International Journal of Medical Robotics and Computer Assisted Surgery, Vol. 9, pp. 109-118, 2013 [PDF].

A. L. Simpson, J. Burgner, C. L. Glisson, S. D. Herrell, B. Ma, R. J. Webster III, and M. I. Miga,  "Comparison study of intraoperative surface acquisition methods for surgical navigation", IEEE Transactions on Biomedical Engineering, Vol. 60, No. 4, pp. 1090-1099, 2013 [PDF].

J. Burgner, A. L. Simpson, J. M. Fitzpatrick, R. A. Lathrop, S. D. Herrell, M. I. Miga, and R. J. Webster III, 'A study on the theoretical and practical accuracy of conoscopic holography-based surface measurements: toward image registration in minimally invasive surgery', International Journal of Medical Robotics and Computer Assisted Surgery, DOI: 10.1002/rcs.1446, 2013  [PDF].

A. M. Coffey, M. I. Miga, I. Chen, and R. C. Thompson,  "Toward a preoperative planning tool for brain tumor resection therapies", Int. J. Computer Assisted Radiology, DOI 10.1007/s/11548-012-0693-6, pp.1-11, 2013 [PDF]

A. L. Simpson, N. P. Dillon, M. I. Miga, and B. Ma, "A framework for measuring TRE at the tip of an optically tracked pointing stylus", SPIE 2013 Medical Imaging: Image-Guided Procedures, Robotic Interventions, (in press), 2013 [PDF].

T. S. Pheiffer, A. L. Simpson, J. E. Ondrake, and M. I. Miga, "Geometric reconstruction using tracked ultrasound strain imaging", SPIE 2013 Medical Imaging: Image-Guided Procedures, Robotic Interventions, (in press), 2013 [PDF].

J. A. Weis, M. I. Miga, L. R. Arlinghaus, X. Li, A. B. Chakravarthy, V. G. Abramson, J. Farley, and T. E. Yankeelov,  "A mechanically coupled reaction-diffusion model for predicting the response of breast cancer to neoadjuvant chemotherapy", Int. Society of Magnetic Resonance in Medicine: 21st Annual Meeting & Exhibition, Salt Lake City, Utah, 2013 [PDF].

J. A. Weis, T. E. Yankeelov, S. A. Munoz, R. A. Sastry, S. L. Barnes, L. R. Arlinghaus, X. Li, and M. I. Miga, "A consistent pre-clinical/clinical elastography approach for assessing tumor mechanical properties in therapeutic systems", SPIE 2013 Medical Imaging: Biomedical Applications in Molecular, Structural, and Functional Imaging, (in press), 2013  [PDF].

J. A. Weis, M. I. Miga, X. Li, L. R. Arlinghaus, A. B. Chakavarthy, V. Abramson, R. G. Abramson, J. Farley, and T. E. Yankeelov, "A mechanically coupled reaction diffusion model of breast tumor response during neoadjuvant chemotherapy", SPIE 2013 Medical Imaging: Biomedical Applications in Molecular, Structural, and Functional Imaging, (in press), 2013 [PDF].

I. Chen, A. L. Simpson, K. Sun, R. C. Thompson, and M. I. Miga, "Sensitivity analysis and automation for intraoperative implementation of the atlas-based method for brain shift correction", SPIE 2013 Medical Imaging: Image-Guided Procedures, Robotic Interventions, (in press), 2013 [PDF].

D. C. Rucker, Y. Wu, J. E. Ondrake, T. S. Pheiffer, A. L. Simpson, and M. I. Miga, "Nonrigid liver registration for image-guided surgery using partial surface data: A novel iterative approach", SPIE 2013 Medical Imaging: Image-Guided Procedures, Robotic Interventions, (in press), 2013[PDF].  

A. N. Kumar, T. S. Pheiffer, A. L. Simpson, R. C. Thompson, M. I. Miga, and B. M. Dawant, "Phantom-based comparison of the accuracy of point clouds extracted from stereo cameras and laser range scanner", SPIE 2013 Medical Imaging: Image-Guided Procedures, Robotic Interventions, (in press), 2013 [PDF].

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Publications 2012

J. A. Weis, F. Granero-Molto, T. J. Myers, L. Longobardi, A. Spagnoli, and M. I. Miga, "Comparison of microCT and an inverse finite element approach for biomechanical analysis: Results in a mesenchymal stem cell therapeutic system for fracture healing", Journal of Biomechanics, Vol. 45, No. 12, pp. 2164-2170, 2012 [PDF].

R. G. Abramson, L. R. Arlinghaus, J. A. Weis, X. Li, A. N. Dula, E. Y. Chekmenev, S. A. Smith, M. I. Miga, V. G. Abramson, and T. E. Yankeelov, "Current and emerging quantitative magnetic resonance imaging methods for assessing and predicting the response of breast cancer to neoadjuvant therapy", Breast Cancer: Targets and Therapy, Vol. 4, pp. 139-154, 2012 [PDF].

T. S. Pheiffer, A. L. Simpson, B. Lennon, R. C. Thompson, and M. I. Miga, "Design and evaluation of an optically-tracked single-CCD laser range scanner", Medical Physics, Vol. 39, No. 2, pp. 636-642, 2012 [PDF].

R. L. Galloway, S. Duke, and M. I. Miga, "Image-guided abdominal surgery and therapy delivery", Journal of Healthcare Engineering, Vol. 3, No. 3, pp. 203-228, 2012 [PDF].

M. J. Shannon, I. M. Meszoely, T. S. Pheiffer, A. L. Simpson, K. Sun, J. E. Ondrake, and M. I. Miga, "Initial study of breast tissue reiteration toward image-guided breast  surgery", SPIE 2012 Medical Imaging: Image-Guided Procedures, Robotic Interventions, and Modeling Conference, (in press), 2012 [PDF].

K. Sun, W. J. Rodriguez, S. Pallavaram, B. M. Dawant, and M. I. Miga, "Optimizing the delivery of deep brain stimulation using electrophysiological atlases and an inverse modeling approach", SPIE 2012 Medical Imaging: Image-Guided Procedures, Robotic Interventions, and Modeling Conference, (in press), 2012 [PDF].

A. L. Simpson, J. Burgner, I. Chen, T. S. Pheiffer, K. Sun, R. C. Thompson, R. J. Webster, and M. I. Miga, "Intraoperative brain resection cavity characterization with conoscopic holography", SPIE 2012 Medical Imaging: Image-Guided Procedures, Robotic Interventions, and Modeling Conference, (in press), 2012 [PDF].

K. E. Miller, J. E. Ondrake, T. S. Pheiffer, A. L. Simpson, and M. I. Miga, "Utilizing ultrasound as a surface digitization tool in image guided liver surgery", SPIE 2012 Medical Imaging: Image-Guided Procedures, Robotic Interventions, (in press), 2012 [PDF].  

P. J. Swaney, J. Burgner, T. S. Pheiffer, D. C. Rucker, H. B. Gilbert, J. E. Ondrake, A.  L. Simpson, E. C. Burdette, M. I. Miga, and R. J. Webster, "Tracked 3D ultrasound targeting with an active cannula", SPIE 2012 Medical Imaging: Image-Guided Procedures, Robotic Interventions, (in press), 2012 [PDF].

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Publications 2011

T. S. Pheiffer, J. J. Ou, R. E. Ong, and M. I. Miga, 'Automatic generation of boundary conditions using demons non-rigid image registration for use in 3D modality-independent elastography', IEEE Transactions on Biomedical Engineering, Vol. 58, No. 9, pp. 2607-2616, 2011 [PDF].

L. W. Clements, P. Dumpuri, W. C. Chapman, B. M. Dawant, R. L. Galloway, and M. I. Miga, 'Organ surface deformation measurement and analysis in open hepatic surgery: Method and preliminary results from 12 clinical cases', IEEE Transactions on Biomedical Engineering, Vol. 58, No. 8, 2011 [PDF].

S. Ding, M. I. Miga, T. S. Pheiffer, A. L. Simpson, R. C. Thompson, and B. M. Dawant, 'Tracking of vessels in intra-operative microscope video sequences for cortical displacement estimation', IEEE Transactions on Biomedical Engineering, Vol. 58, No. 7, pp. 1985-1993, 2011 [PDF].

H. O. Altamar, R. E. Ong, C. L. Glisson, D. P. Viprakasit, M. I. Miga, S. D. Herrell, R. L. Galloway, 'Kidney deformation and intraprocedural registration: A study of elements of image-guided kidney surgery', Journal of Endourology, Vol. 25, No. 3, pp. 511-517, 2011 [PDF].

I. Chen, A. M. Coffey, S. Y. Ding, P. Dumpuri, B. M. Dawant, R. C. Thompson, and M. I. Miga, 'Intraoperative brain shift compensation: Accounting for dural septa', IEEE Transactions on Biomedical Engineering,Vol. 58, No. 3, pp. 499-508, 2011 [PDF].

M. I. Miga, P. Dumpuri, A. L. Simpson, J. A. Weis, and W. R. Jarnagin, 'The sparse data extrapolation problem: Strategies for soft-tissue correction for image-guided liver surgery', SPIE 2011 Medical Imaging: Visualization, Image-Guided Procedures, and Modeling Conference', Editors: K. H. Wong and D. R. Holmes III, Vol. 7964, 2011 [PDF].

A. L. Simpson, B. Ma, R. E. Ellis, A. J. Stewart, and M. I. Miga, 'Uncertainty propagation and analysis of image-guided surgery', SPIE 2011 Medical Imaging: Visualization, Image-Guided Procedures, and Modeling Conference, Editors: K. H. Wong and D. R. Holmes III, Vol. 7964, 2011 [PDF].

T. S. Pheiffer, B. Lennon, A. L. Simpson, and M. I. Miga, 'Development of a novel laser range scanner', SPIE 2011 Medical Imaging: Visualization, Image-Guided Procedures, and Modeling Conference, Editors: K. H. Wong and D. R. Holmes III, Vol. 7964, 2011 [PDF].

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Publications 2010

P. Dumpuri, L. W. Clements, B. M. Dawant, and M. I. Miga, 'Model-updated image-guided liver surgery: Preliminary results using surface characterization', Progress in Biophysics and Molecular Biology, Vol. 103, Issues 2-3, pp. 197-207, 2010 [PDF].

R. Ong, J. J. Ou, and M. I. Miga, 'Non-rigid registration of breast surfaces using the laplace and diffusion equations', Biomedical Engineering Online, Vol 9., No. 8, 2010 [PDF].

J. A. Weis, M. I. Miga, F. Granero-Molto, and A. Spagnoli, 'A finite element inverse analysis functional improvement during the fracture healing process', Journal of Biomechanics , Vol. 43, No. 3, pp. 557-562, 2010 [PDF].

P. Dumpuri, R. C. Thompson, A. Cao, S. Ding, I. Garg, B. M. Dawant, and M. I. Miga, 'A fast efficient method to compensate for brain shift for tumor resection therapies measured between preoperative and postoperative tomograms', IEEE Transactions on Biomedical Engineering, Vol. 57, No. 6, pp. 1285-1296, 2010 [PDF].

F. Granero-Molto, T. J. Myers, J. A. Weis, Y. Yan, T. Li, L. Longobardi, M. I. Miga, A. Spagnoli, 'Mesenchymal stem cells expressing IGF-I improve fracture repair: The seed and the soil for tissue regeneration', Endocrine Reviews, Vol. 31, No. 3, Suppl. 1, 2010.

M. I. Miga, J. A. Weis, F. Granero-Molto, A. Spagnoli, "Quantifying mechanical properties in a murine fracture healing system using an inverse geometric nonlinear elasticity modeling framework", 5th International Symposium on Biomedical Simulation, Lecture Notes in Computer Science, Ed. F. Bello and S. Cotin, Vol. 5958, pp. 29-37, 2010  [PDF].

I. Garg, S. Ding, A. M. Coffey, P. Dumpuri, R. C. Thompson, B. M. Dawant, M. I. Miga, "Enhancement of subsurface brain shift model accuracy: a preliminary study", SPIE Medical Imaging 2010: Visualization, Image-Guided Procedures, and Modeling Conference, Vol.  7625, 2010 [PDF].

T. S. Pheiffer, J. J. Ou, M. I. Miga, "Automatic generation of boundary conditions using Demons non-rigid image registration for use in 3D modality independent elastography", SPIE Medical Imaging 2010: Visualization, Image-Guided Procedures, and Modeling Conference, Vol.  7625, 2010  [PDF].

P. Dumpuri, L. W. Clements, B. M. Dawant, M. I. Miga, "Model-updated image-guided liver surgery: preliminary results using intra-operative surface characterization", SPIE Medical Imaging 2010: Visualization, Image-Guided Procedures, and Modeling Conference, Vol.  7625, 2010  [PDF].

M. I. Miga, J. A. Weis, F. Granero-Molto, A. Spagnoli, "Quantifying mechanical properties in a murine fracture healing system using inverse modeling: preliminary work", SPIE Medical Imaging 2010: Biomedical Applications in Molecular, Structural, and Functional Imaging, Vol.  7626, 2010  [PDF].

A. M. Coffey, R. C. Thompson, M. I. Miga, "An evaluative tool for preoperative planning of brain tumor resection", SPIE Medical Imaging 2010: Visualization, Image-Guided Procedures, and Modeling Conference, Vol.  7625, 2010  [PDF].

J.A. Weis, F. Granero-Molt", T. Myers, A. Spagnoli, and M.I. Miga, "A novel inverse finite element analysis to assess bone fracture healing in mice receiving bone marrow mesenchymal stem cell transplantation", Proc. Biomedical Engineering Society Conference 2010, 10/6-9/10, Austin, TX, 2010 [PDF].

S. L. Barnes, and M. I. Miga, "Application of a soft tissue modulus evaluation assay to breast tumor tissue", Proc. Biomedical Engineering Society Conference 2010, 10/6-9/10, Austin, TX, 2010 [PDF].

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Publications 2009

F. Granero-Molto, J. A. Weis, M. I. Miga, B. Landis, T. J. Myers, L. O'Rear, L. Longobardi, E. D. Jansen, D. P. Mortlock, A. Spagnoli, 'Regenerative effects of transplanted mesenchymal stem cells in fracture healing', Stem Cells, Vol. 27, No. 8, pp. 1887-1898, 2009 [PDF].

S. L. Barnes, P. P. Young, M. I. Miga, 'A novel model-gel-tissue assay analysis for comparing tumor elastic properties to collagen content', Biomechanics and Modelling in Mechanobiology, Vol. 8, No. 4, pp. 337-343, 2009 [PDF].

C.C. R. Chen, M. I. Miga, and R. L. Galloway, 'Optimizing electrode placement using finite-element models in radiofrequency ablation treatment planning',  IEEE Transactions on Biomedical Engineering, Vol. 56, No. 2, 2009 [PDF].

S. Ding, M. I. Miga, J. H. Noble, A. Cao, P. Dumpuri, R. C. Thompson, and B. M. Dawant, 'Semi-automatic registration of pre- and postbrain tumor resection laser range data: Method and validation',  IEEE Transactions on Biomedical Engineering, Vol. 56, No. 3, 2009 [PDF].

S. Ding, M. I. Miga, R. C. Thompson, and B. M. Dawant, 'Robust vessel registration and tracking of microscope video images in tumor resection neurosurgery', IEEE International Symposium on Biomedical Imaging (ISBI): From Nano to Macro, pp. 1043-1046, 2009 [PDF].

R. Ong, C. L. Glisson, S. D. Herrel, M. I. Miga, R. L. Galloway, "A deformation model for non-rigid registration of the kidney", SPIE Medical Imaging 2009: Visualization, Image-Guided Procedures, and Modeling Conference, (in press), 2009 [PDF].

P. Dumpuri, L. W. Clements, R. Li, J. M. Waite, J. D. Stefansic, D. A. Geller, M. I. Miga, B. M. Dawant, 'Comparison of pre/post-operative CT image volumes to preoperative digitization of partial hepatectomies: A feasibility study in surgical validation', SPIE Medical Imaging 2009: Visualization, Image-Guided Procedures, and Modeling Conference, (in press), 2009 [PDF].

S. Ding, M. I. Miga, R. C. Thompson, I. Garg, B. M. Dawant, 'Automatic segmentation of cortical vessels in pre- and post- tumor resection laser range scan images', SPIE Medical Imaging 2009: Visualization, Image-Guided Procedures, and Modeling Conference, (in press), 2009 [PDF].

D. Hackworth, P. Dumpuri, and M. I. Miga, 'A dual compute resource strategy for computational model-assisted therapeutic interventions', SPIE Medical Imaging 2009: Visualization, Image-Guided Procedures, and Modeling Conference, (in press), 2009 [PDF].

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Publications 2008

L. W. Clements, W. C. Chapman, B. M. Dawant, R. L. Galloway, and M. I. Miga, 'Robust surface registration using salient anatomical features for image-guided liver surgery: Algorithm and validation',  Medical Physics, Vol. 35, No. 6, pp. 2528-2540, 2008 [PDF].

(**And Selected For) L. W. Clements, W. C. Chapman, B. M. Dawant, R. L. Galloway, and M. I. Miga, 'Robust surface registration using salient anatomical features for image-guided liver surgery: Algorithm and validation',  Virtual Journal of Biological Physics Research, Vol. 15, Issue 11, June1, 2008[http://scitation.aip.org/dbt/dbt.jspKEY=VIRT02&Volume=CURVOL&Issue=CURISS].

A. Cao, R. C. Thompson, P. Dumpuri, B. M. Dawant, R. L. Galloway, S. Ding, and M. I. Miga, 'Laser range scanning for image-guided neurosurgery: Investigation of image-to-physical space registrations', Medical Physics, Vol. 35, No. 4, pp. 1593-1605, 2008 [PDF].

J. J. Ou, R. E. Ong, T. E. Yankeelov, and M. I. Miga, 'Evaluation of 3D modality-independent elastography for breast imaging: a simulation study', Physics in Medicine and Biology, Vol. 53, No. 1, pp. 147-163, 2008 [PDF].

I. Garg, and M. I. Miga, "Preliminary investigation of the inhibitory effects of mechanical stress in tumor growth", SPIE Medical Imaging 2008: Visualization, Image-Guided Procedures, and Modeling Conference, Vol. 6918, 2008 [PDF].

R. Ong, S. Duke Herrel, M. I. Miga, R. L. Galloway, "A kidney deformation model for use in non-rigid registration during image-guided surgery", SPIE Medical Imaging 2008: Visualization, Image-Guided Procedures, and Modeling Conference, Vol. 6918, 2008 [PDF].

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Publications 2007

F. Granero-Molto, J. A. Weis, L. D. O'Rear, M. I. Miga, and A. Spagnoli, 'IGF-I engineered bone marrow mesenchymal stem cells improve the fracture healing process', Journal of Bone and Mineral Research, Vol. 22, Suppl., pp. S105, 2007.

J. A. Weis, F. Granero-Molto, L. D. O'Rear, M. I. Miga, and A. Spagnoli, 'Development of a high-resolution 3D micro-CT based model to predict fracture callus histological architecture', Journal of Bone and Mineral Research, Vol. 22, Suppl., pp. S483, 2007.

S. L. Barnes, A. Lyshchik, M. K. Washington, J. C. Gore, and M. I. Miga, 'Development of a mechanical testing assay for fibrotic murine liver', Medical Physics, Vol. 34, No. 11, pp. 4439-4450, 2007 [PDF].

C. R. Chen, M. I. Miga, R. L. Galloway, 'Characterization of tracked radiofrequency ablation in phantom', Medical Physics, Vol. 34, No. 10, pp. 4030-4040, 2007 [PDF].

D. M. Cash, M. I. Miga, S. C. Glasgow, B. M. Dawant, L. W. Clements, Z. Cao, R. L. Galloway, W. C. Chapman, 'Concepts and preliminary data toward the realization of image-guided liver surgery', Journal of Gastrointestinal Surgery, Vol. 11, No. 7, pp. 844-859, 2007 [PDF].

A. Lyshchik, R. Moses, S. L. Barnes, T. Higashi, R. Asato, M. I. Miga, J. C. Gore, A. C. Fleischer 'Quantitative analysis of tumor vascularity in benign and malignant solid thyroid nodules', Journal of Ultrasound in Medicine, Vol. 26, pp. 837-846, 2007 [PDF].

P. Dumpuri, R. C. Thompson, B. M. Dawant, A. Cao, M. I. Miga, 'An atlas-based method to compensate for brain shift: Preliminary results', Medical Image Analysis, Vol. 11, No. 2., pp.128-145, 2007 [PDF].

D.M. Kwartowitz, S.D. Herrell, R.L. Galloway, 'Update: toward image-guided robotic surgery: determining the intrinsic accuracy of the daVinci-S robot', International Journal of Computer Assisted Radiology and Surgery, (in press), 2007.

S. L. Barnes, A. Lyschik, J. C. Gore, M. I. Miga, 'Development of a mechanical assay for modulus analysis of fibrotic murine livers', 6th International Conference on the Ultrasonic Measurement and Imaging of Tissue Elasticity, Sante Fe, New Mexico, pg. 48, 11/2-5/2007 [PDF].

M. I. Miga, J. J. Ou, S. L. Barnes, A. Lyschik, J. C. Gore, 'Modality independent elastography: Initial results with a murine fibrosis model', 6th International Conference on the Ultrasonic Measurement and Imaging of Tissue Elasticity, Sante Fe, New Mexico, pg. 118, 11/2-5/2007 [PDF].

J. A. Weis, F. Granero-Molto, L. D. O"Rear, M. I. Miga, A. Spagnoli, "Development of a high-resolution 3D microCT based model to predict fracture callus histological architecture", American Society for Bone and Mineral Research Conference, 6/2007.

F. Granero-Molto, J. A. Weis, L. D. O"Rear, M. I. Miga, A. Spagnoli, "IGF-I engineered bone marrow mesenchymal stem cells improve the fracture healing process", American Society for Bone and Mineral Research Conference, 6/2007.

A. Cao, M. I. Miga, P. Dumpuri, S. Ding, B. M. Dawant, R. C. Thompson, 'Target error for image-to-physical space registration: Preliminary clinical results using laser range scanning', Medical Imaging 2007: Visualization and Image-Guided Procedures: Proc. of SPIE, (in press), 2007 [PDF].

S. Ding, M. I. Miga, R. C. Thompson, P. Dumpuri, A. Cao, B. M. Dawant, 'Estimation of intra-operative brain shift using a tracked laser range scanner', 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2007. EMBS 2007, pp. 848-851, 8/22-26, 2007 [PDF].

L. W. Clements, P. Dumpuri, W. C. Chapman, R. L. Galloway, Jr., and M. I. Miga, 'Atlas-based method for model updating in image-guided liver surgery', Medical Imaging 2007: Visualization and Image-Guided Procedures: Proc. of SPIE, (in press), 2007 [PDF].

D.M. Kwartowitz, M.I. Miga, S.D. Herrell, R.L. Galloway, 'Toward image-guided robotic surgery: multi-arm tracking through hybrid localization', Computer Assisted Radiology and Surgery, 21st International Congress and Exhibition, (in press), June 25-30, Berlin, Germany, 2007.

M. I. Miga, J. J. Ou, and D. L. Ellis, 'An elastography framework for use in dermoscopy', Medical Imaging 2007: Physiology, Function and Structure from Medical Images: Proc. of the SPIE, (in press), 2007 [PDF] .

I. Garg, L.W. Clements, and R.L. Galloway, 'A computational approach to pre-align point cloud data for surface registration in image guided liver surgery', Medical Imaging 2007: Visualization and Image-Guided Procedures: Proc. of the SPIE, (in press), 2007 [PDF].

J. J. Ou, R. E. Ong, and M. I. Miga, 'An Evaluation of 3D Modality Independent Elastography Robustness to Boundary Condition Noise', Medical Imaging 2007: Physiology, Function and Structure from Medical Images: Proc. of the SPIE, (in press), 2007 [PDF].

R. E. Ong, J. J. Ou, M. I. Miga, 'Using Laplace's Equation for Non-Rigid Registration of Breast Surfaces', Medical Imaging 2007: Visualization and Image-Guided Procedures: Proc. of the SPIE, (in press), 2007 [PDF].

K. Ha, P. Dumpuri, M. I. Miga, R. C. Thompson, 'Modeling surgical procedures to assist in understanding surgical approach', Medical Imaging 2007: Visualization and Image-Guided Procedures: Proc. of the SPIE, (in press), 2007 [PDF] .

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Publications 2006

T. K. Sinha, M. I. Miga, D. M. Cash, and R. J. Weil, 'Intraoperative cortical surface characterization using laser range scanning: Preliminary results', Neurosurgery, Vol. 59, No. 4, pp. 368-377, 2006 [PDF].

S. Ding, M. I. Miga, R. C. Thompson, B. M. Dawant, "Non-rigid registration of laser-range scanner in Image Guided Surgery", Vanderbilt University Institute of Imaging Science Research Retreat, June 25-27, Louisville, KY, 2006.[PDF]

SPIE Medical Imaging 2006: Short Course on Image-Guided Procedures and Computer Aided Surgery:  Bob Galloway [PDF], Kevin Cleary [PDF], Kenneth Wong [PDF], Filip Banovac [PDF], Michael I. Miga [PDF]

L. W. Clements, D. M. Cash, W. C. Chapman, R. L. Galloway, and M. I. Miga, "Robust surface registration using salient anatomical features in image-guided liver surgery", Medical Imaging 2006: Visualization, Image-guided Procedures, and Display: Proc. of the SPIE, (in press), 2006 [PDF].

C. R. Chen, M. I. Miga, and R. L. Galloway, "Optimizing needle placement in radiofrequency ablation treatment planning", Medical Imaging 2006: Visualization, Image-guided Procedures, and Display: Proc. of the SPIE, (in press), 2006 [PDF].

P. Dumpuri, R. C. Thompson, T. K. Sinha, M. I. Miga, 'Automated brain shift correcction using a pre-computed deformation atlas', Medical Imaging 2006: Visualization, Image-guided Procedures, and Display: Proc. of the SPIE, (in press), 2006 [PDF].

D. R. Schuler III, J. J. Ou, S. L. Barnes, and M. I. Miga, "Automatic surface correspondence methods for a deformed breast", Medical Imaging 2006: Visualization, Image-guided Procedures, and Display: Proc. of the SPIE, (in press), 2006 [PDF].

T. K. Sinha, and M. I. Miga, 'Investigation of a block matching algorithm for determining spatial constraints in morphometric analysis', Medical Imaging 2006: Physiology, Function and Structure from Medical Images: Proc. of the SPIE, (in press), 2006 [PDF].

J. J. Ou, S. L. Barnes, and M. I. Miga, 'Application of Multi-resolution Modality Independent Elastography for Detection of Multiple Anomalous Objects', Medical Imaging 2006: Physiology, Function and Structure from Medical Images: Proc. of the SPIE, (in press), 2006 [PDF].

J. J. Ou, S. L. Barnes, and M. I. Miga, 'Preliminary testing of sensitivity to input data quality in an elastographic reconstruction method', International Symposium on Biomedical Imaging 2006, (in press), 2006 [PDF].

A. Cao, P. Dumpuri, and M. I. Miga, 'Tracking cortical surface deformations based on vessel structure using a laser range scanner', International Symposium on Biomedical Imaging 2006, (in press), 2006 [PDF].

D. Knaus, E. Friets, J. Bieszczad, C. R. Chen, M. I. Miga, R. L. Galloway, D. B. Kynor, 'Tracking cortical surface deformations based on vessel structure using a laser range scanner', International Symposium on Biomedical Imaging 2006, (in press), 2006 [PDF].

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Publications 2005

D. M. Cash, M. I. Miga, T. K. Sinha, R. L. Galloway, and W. C. Chapman, "Compensating for intra-operative soft tissue deformations using incomplete surface data and finite elements", IEEE Transactions on Medical Imaging, vol. 24, no. 11, pp. 1479-1491, 2005. [PDF]

M. I. Miga, M. P. Rothney, J. J. Ou, "Modality independent elastography (MIE):  Potential applications in dermoscopy", Medical Physics, vol. 32, no. 5, pp. 1308-1320, 2005. [PDF]

T. K. Sinha, B. M. Dawant, V. Duay, D. M. Cash, R. J. Weil, and M. I. Miga, "A method to track cortical surface deformations using a laser range scanner", IEEE Transactions on Medical Imaging, vol. 24, no. 6, pp. 767-781, 2005. [PDF]

P. Dumpuri, T. K. Sinha, and M. I. Miga, "Intraoperative registration for cortical surface characterization", Vanderbilt University Institute of Imaging Science Research Retreat, June 12-14,  Memphis, TN, 2005. [PDF]

J. J. Ou, S. L. Barnes, and M. I. Miga, "Evaluating dermoscopic applications for modality independent elastography", Vanderbilt University Institute of Imaging Science Research Retreat, June 12-14, Memphis, TN, 2005. [PDF]

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Publications - 2004

C. W. Washington, and M. I. Miga, "Modality Independent Elastography (MIE):  A New Approach to Elasticity Imaging", IEEE Transactions on Medical Imaging, Vol. 23, No. 9, pp. 1117-1128, 2004. [PDF]

M. P. Rothney, C. W. Washington, and M. I. Miga, "Evaluation of a Similarity-Based Elastography Technique using Four Similarity Metrics", 2004 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, pp. 696-699, 4/2004. [PDF]

M. I. Miga, "Modality Independent Elastography", The Whitaker Foundation: Biomedical Engineering Research Conference, August 12-15, 2004. [PDF]

C. W. Washington, and M. I. Miga, "Modality Independent Elastography:  Preliminary Results", Medical Imaging 2004: Image Processing: Proc. of the SPIE, Vol. 5370, pp. 1380-1387, 2004. [PDF]

D. M. Cash, T. K. Sinha, C. C. Chen, B. M. Dawant, W. C. Chapman, M. I. Miga, R. L. Galloway, "Identification of deformation using invariant surface information", Medical Imaging 2004: Visualization, Image-guided Procedures, and Display: Proc. of the SPIE, Vol. 5029, pp. 269-280, 2004. [PDF]

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Publications - 2003

M. I. Miga, A new approach to elastography using mutual information and finite elements, Physics in Medicine and Biology, vol. 48, no. 4, pp. 467-480, 2003. [PDF]

D. M. Cash, T. K. Sinha, W. C. Chapman, H. Terawaki, B. M. Dawant, R. L. Galloway, M. I. Miga, "Incorporation of a laser range scanner into image-guided liver surgery: surface acquisition, registration, and tracking", Medical Physics, vol. 30, no. 7., pp. 1671-1682, 2003. [PDF]

M. I. Miga, T. K. Sinha, D. M. Cash, R. L. Galloway, and R. J. Weil, "Cortical surface registration for image-guided neurosurgery using laser-range scanning", IEEE Transactions on Medical Imaging, vol. 22, no. 8, pp.973-985, 2003. [PDF]

V. Duay, T. K. Sinha, P. D"Haese, M. I. Miga, B. M. Dawant, "Non-rigid registration of serial intra-operative images for automatic brain-shift estimation", Lecture Notes in Computer Science: Second International Workshop on Biomedical Image Registration " WBIR 2003, Vol. 2717, pp.  61-70, 2003. [PDF]

T. K. Sinha, V. Duay, B. M. Dawant, M. I. Miga, "Cortical shift tracking using a laser range scanner and deformable registration methods", Lecture Notes in Computer Science: Medical Image Computing and Computer-Assisted Intervention " MICCAI 2003, Vol. 2879, Part 2, pp. 166-174, 2003.  [PDF]

P. Dumpuri, R. C. Chen, M. I. Miga, "Model updated image guidance: A statistical approach", Lecture Notes in Computer Science: Medical Image Computing and Computer-Assisted Intervention " MICCAI 2003, Vol. 2879, Part 1, pp. 375-382, 2003. [PDF]

M. I. Miga, "Modality Independent Elastography", The Whitaker Foundation: Biomedical Engineering Research Conference, August 7-10, 2003. [PDF]

B. K. Lamprich and M. I. Miga, "Analysis of model-updated MR images to correct for brain deformation due to tissue retraction", Medical Imaging 2003: Visualization, Image-guided Procedures and Display: Proc. of the SPIE, Vol. 5029, pp. 552-560, 2003. [PDF]

M. I. Miga, D. M. Cash, Z. Cao, R. L. Galloway, B. Dawant, W. C. Chapman, "Intraoperative registration of the liver for image-guided surgery using laser range scanning and deformable models", Medical Imaging 2003: Visualization, Image-guided Procedures, and Display: Proc. of the SPIE, Vol. 5029, pp. 350-359, 2003. [PDF]

T. K. Sinha, D. M. Cash, R. J. Weil, R. L. Galloway, M. I. Miga, "Laser range scanning for cortical surface characterization during neurosurgery", Medical Imaging 2003: Visualization, Image-guided Procedures, and Display: Proc. of the SPIE, Vol. 5029, pp. 98-107, 2003. [PDF]

D. M. Cash, T. K. Sinha, R. L.Galloway, W. C. Chapman, H. Terawaki, M. I. Miga, "Incorporation of a laser range scanner into an image-guided surgical system", Medical Imaging 2003: Visualization, Image-guided Procedures and Display: Proc. of the SPIE, Vol. 5029, pp.269-280, 2003. [PDF]

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Publications - 2002

M. I. Miga, T. E. Kerner, T. M. Darcey, Source localization using finite elements and targeted simulated annealing. IEEE Transactions on Biomedical Engineering, vol. 49, pp. 743-745, 2002. [PDF]

L. A. Platenik, M. I. Miga, D. W. Roberts, K. E. Lunn, F. E. Kennedy, A. Hartov, K. D. Paulsen. In vivo quantification of retraction deformation modeling for updated image-guidance during neurosurgery. IEEE Trans. on Biomedical Engineering, vol. 49, no. 8, pp. 823-835, 2002. [PDF]

T. K. Sinha, D. M. Cash, R. J. Weil, R. L. Galloway, M. I. Miga, "Cortical surface registration using texture mapped point clouds and mutual information", Lecture Notes in Computer Science: Medical Image Computing and Computer-Assisted Intervention " MICCAI 2002, Springer Verlag, New York, Vol. 2488, Part 2, pp. 533-540, 2002. [PDF]

T. K. Sinha, D. M. Cash, R. J. Weil, R. L. Galloway, M. I. Miga. Textured laser range scanning and registration of the cortical surface. 24th Annual International Conf. Of EMBS and BMES, 2002. [PDF]

D. M. Cash, T. Sinha, W. Chapman, R. L. Galloway Jr., M. I. Miga. Fast, Accurate Surface Acquisition Using a Laser Range Scanner for Image-Guided Liver Surgery. Medical Imaging 2002: Visualization, Display, and Image-guided Procedures: Proc. of the SPIE, 2002. [PDF]

M. I. Miga, A New Approach to Elastographic Imaging: Modality Independent Elastography. Medical Imaging 2002: Image Processing, vol. 3, no. 22, pp. 604-611, 2002. [PDF]

M. I. Miga, Modality independent elastography. Proc. of the 5th Tennessee Conference on Biomedical Engineering, pp. 36, 2002. [PDF]

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Publications - 2001

M. I. Miga, D. W. Roberts, F. E. Kennedy, L. A. Platenik, A. Hartov, K. E. Lunn, K. D. Paulsen. Modeling of retraction and resection for intraoperative updating of images during surgery. Neurosurgery, vol. 49, no. 1, 2001. [PDF]

P. M. Meaney, K. D. Paulsen, B. W. Pogue, M. I. Miga, Microwave image reconstruction utilizing log-magnitude and unwrapped phase to improve high-contrast object recovery. IEEE Transactions on Medical Imaging, vol. 20, no. 2, pp. 104-116, 2001. [PDF]

E. E. W. Van Houten, M. I. Miga, J. B. Weaver, F. E. Kennedy, K. D. Paulsen, A three-dimensional subzone based reconstruction algorithm for MR elastography. Magnetic Resonance in Medicine, vol. 45, no. 5, pp. 827-837, 2001. [PDF]

J. B. Weaver, E. E. W. Van Houten, M. I. Miga, F. E. Kennedy, and K. D. Paulsen, Magnetic resonance elastography using 3D gradient echo measurements of steady-state motion. Medical Physics, vol. 28, no. 8, pp. 1620-1628, 2001. [PDF]

M. I. Miga, J. M. Fitzpatrick, R. L. Galloway Jr., K. D. Paulsen. Incorporation of surface-based deformations for updating images intraoperatively. Medical Imaging 2001: Visualization, Display, and Image-guided Procedures, vol. 2, no. 24, pp. 169-178, 2001. [PDF]

K. D. Paulsen, M. I. Miga, D. W. Roberts, F. E. Kennedy, L. A. Platenik, K. E. Lunn, A. Hartov. Finite element modeling of tissue retraction and resection for preoperative neuroimage compensation concurrent with surgery. Medical Imaging 2001: Visualization, Display, and Image-guided Procedures vol. 2, no. 24, pp. 13-21, 2001. [PDF]

L. A. Platenik, M. I. Miga, D. W. Roberts, F. E. Kennedy, A. Hartov, K. E. Lunn, K. D. Paulsen. In vivo comparison of an incremental vs. single-step retraction model for intraoperative compensation. Medical Imaging 2001: Visualization, Display, and Image-guided Procedures, vol. 2, no. 24, pp. 358-365, 2001. [PDF]

K. E. Lunn, A. Hartov, F. E. Kennedy, M. I. Miga, D. W. Roberts, L. A. Platenik, K. D. Paulsen. Intraoperative ultrasound as sparse data for brain deformation modeling. Medical Imaging 2001: Visualization, Display, and Image-guided Procedures: Proc. of the SPIE,"2001. [PDF]

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Publications - 2000

M. I. Miga, K. D. Paulsen, P. J. Hoopes, F. E. Kennedy, A. Hartov, and D. W. Roberts. In vivo analysis and modeling of interstitial pressure in the brain under surgical loading. Journal of Biomechanical Engineering, Vol. 122, No. 4, pp. 354-363, 2000. [PDF]

M. I. Miga, K. D. Paulsen, F. E. Kennedy, P. J. Hoopes, A. Hartov, and D. W. Roberts. In vivo analysis of heterogeneous brain deformation computations for model-updated image guidance. Computer Methods in Biomechanics and Biomedical Engineering, vol.3, no. 2, pp. 129-146, 2000. [PDF]

M. I. Miga, K. D. Paulsen, F. E. Kennedy, P. J. Hoopes, A. Hartov, and D. W. Roberts. In vivo quantification of a homogeneous brain deformation model for updating preoperative images during surgery. IEEE Transactions on Biomedical Engineering, vol. 47, no. 2, pp. 266-273, 2000. [PDF]

E. E. W. Van Houten, J. B. Weaver, M. I. Miga, F. E. Kennedy, and K. D. Paulsen, Elasticity reconstruction from experimental MR displacement data: initial experience with an overlapping subzone finite element inversion process. Medical Physics, vol. 28, no. 1, pp. 101-107, 2000. [PDF]

M. I. Miga, A. Staubert, K. D. Paulsen, F. E. Kennedy, V. M. Tronnier, D. W. Roberts, A. Hartov, L. A. Platenik, K. E. Lunn. Model-updated image-guided neurosurgery: Preliminary analysis using intraoperative MR. Medical Image Computing and Computer-Assisted Intervention 2000: Lecture Notes in Computer Science, Springer Verlag, New York, 1935, pp.115-124, 2000. [PDF]

E. E. W. Van Houten, K. D. Paulsen, M. I. Miga, F. E. Kennedy, J. B. Weaver, A subzone based nonlinear inversion scheme for viscoelastic tissue properties. Medical Imaging 2000: Image Processing, Proceedings of the SPIE, Vol. 3979, pp. 556-563, 2000. [PDF]

A. Hartov, M. I. Miga, L. Platenik, D. W. Roberts, F. E. Kennedy, K. D. Paulsen. Validation of a 3D deformation model of the brain during surgery. World Congress on Medical Physics & Biomedical Engineering, Chicago, IL, 7/23-28/2000.

E. E. W. Van Houten, M. I. Miga, F. E. Kennedy, J. B. Weaver, K. D. Paulsen, Three-dimensional reconstructive elastographic imaging. International Society for Magnetic Resonance in Medicine, 8th Scientific Meeting and Exhibition, Denver, pp. 1734, 4/1/00.

J. B. Weaver, E. E. W. Van Houten," M. I. Miga, F. E. Kennedy, K. D. Paulsen, Acquisition of MR elastography measurements using steady state" motion. International Society for Magnetic Resonance in Medicine, 8th Scientific Meeting and Exhibition, Denver, pp. 1733, 4/1/00.

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Publications - 1999

M. I. Miga, K. D. Paulsen, J. M. Lemery, S. Eisner, A. Hartov, F. E. Kennedy, D. W. Roberts. Model-updated image guidance: Initial clinical experience with gravity-induced brain deformation. IEEE Transactions on Medical Imaging, vol. 18, no. 10, pp. 866-874, 1999. [PDF]

M. I. Miga, D. W. Roberts, A. Hartov, S. Eisner, J. Lemery, F. E. Kennedy, K. D. Paulsen. Updated neuroimaging using intraoperative brain modeling and sparse data. Stereotactic and Functional Neurosurgery, vol. 72, pp. 103-106, 1999. [PDF]

D. W. Roberts, M. I. Miga, A. Hartov, S. Eisner, J. M. Lemery, F. E. Kennedy, K. D. Paulsen. Intraoperatively updated neuroimaging using brain modeling and sparse data. Neurosurgery, Vol. 45, No. 5, pp. 1199-1207, November, 1999. [PDF]

A. Hartov, S. D. Eisner, D. W. Roberts, K. D. Paulsen, L. A. Platenik, M. I. Miga. Error analysis for a freehand 3D ultrasound system for neuronavigation. Neurosurgical Focus, vol. 6, no. 3, article 5, 1999. [PDF]

K. D. Paulsen, M. I. Miga, F. E. Kennedy, P. J. Hoopes, A. Hartov, and D. W. Roberts. A computational model for tracking subsurface tissue deformation during stereotactic neurosurgery. IEEE Transactions on Biomedical Engineering, Vol. 46, No. 2, pp. 213-225, 1999. [PDF]

E. E. W. Van Houten, K. D. Paulsen, M. I. Miga, F. E. Kennedy, J. B. Weaver, An overlapping subzone technique for MR based elastic property reconstruction. Magnetic Resonance in Medicine, vol. 42, no. 4, pp. 779-786, 1999. [PDF]

H. Pallatroni, A. Hartov, J. McInernery, L. A. Platenik, M. I. Miga, F. E. Kennedy, K. D. Paulsen, D. W. Roberts, "Coregistered ultrasound as a neurosurgical guide", Stereotactic and Functional Neurosurgery, Vol. 73, No.1-4, pp. 143-147, 1999. [PDF]

M. I. Miga, K. D. Paulsen, F. E. Kennedy, P. J. Hoopes, A. Hartov, and D. W. Roberts. Model-updated image-guided neurosurgery using the finite element method: incorporation of the falx cerebri. Medical Image Computing and Computer-Assisted Intervention 1999: Lecture Notes in Computer Science, Springer Verlag, New York, 1679, pp.900-909, 1999. [PDF]

M. I. Miga, K. D. Paulsen, F. E. Kennedy, A. Hartov, D. W. Roberts. Tissue retraction for model-updated image-guided neurosurgery. Joint International Conference of the IEEE Engineering in Medicine and Biology Society and ASME Biomedical Engineering Society, Atlanta, GA, 1999. [PDF]

M. I. Miga, K. D. Paulsen, F. E. Kennedy, A. Hartov, and D. W. Roberts. A model-guided approach to neuronavigation using sparse intraoperative data. 1999 American Association of Neurological Surgeons, New Orleans, LA, 1999.

E. E. W. Houten, M. I. Miga, F. E. Kennedy, J. B. Weaver, K. D. Paulsen, MRI elastograpy reconstruction using a harmonic elastodynamic model. International Society of Magnetic Resonance in Medicine, Philedelphia, pp. 260, 5/22/99.

J. B. Weaver, E. E. W. Van Houten," M. I. Miga, F. E. Kennedy, A. Hartov, S. P. Poplack, H. M. Nagy, K. D. Paulsen, Measurement of harmonic motion for MR elastography. Proceedings of the Society of Magnetic Resonance, Philadelphia, pp. 1617, 5/99.

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Publications - 1998

M. I. Miga, K. D. Paulsen, F. E. Kennedy. Von Neumann stability analysis of Biot's general two-dimensional theory of consolidation. International Journal of Numerical Methods in Engineering, 43, pp. 955-974, 1998. [PDF]

D. W. Roberts, A. Hartov, F. E. Kennedy, M. I. Miga, K. D. Paulsen. Intraoperative brain shift and deformation: a quantitative analysis of cortical displacement in 28 cases. Neurosurgery, Vol. 32, No. 4, pp. 749-760, October, 1998. [PDF]

M. I. Miga, K. D. Paulsen, F. E. Kennedy, P. J. Hoopes, A. Hartov, and D. W. Roberts. Initial in-vivo analysis of 3D heterogeneous brain computations for model-updated image-guided Neurosurgery. Medical Image Computing and Computer-Assisted Intervention 1998: Lecture Notes in Computer Science, Springer Verlag, New York, 1496, pp.743-752, 1998. [PDF]

M. I. Miga, K. D. Paulsen, F. E. Kennedy, P. J. Hoopes, A. Hartov, and D. W. Roberts. Modeling Surgical Loads to Account for Subsurface Tissue Deformation During Stereotactic Neurosurgery. IEEE SPIE Proceedings of Laser-Tissue Interaction IX, Part B: Soft-tissue Modeling, Vol. 3254, pp. 501-511, 1998. [PDF]

M. I. Miga, K. D. Paulsen, F. E. Kennedy, P. J. Hoopes, A. Hartov, and D. W. Roberts. Quantification of a 3D brain deformation model experiencing a temporal mass expansion. Proceedings of the 24th IEEE Northeast Bioengineering Conference, Hershey, PA, pp. 68-71, 1998. [PDF]

J. B. Weaver, E. E. W. Van Houten," M. I. Miga, K. D. Paulsen, Elasticity estimates using phase contrast MRI measurements of displacement. American Association of Physicists in Medicine (AAPM): Medical Physics, vol. 25, no. 7, part 1, pp. A212, 7/98.

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Publications - 1997

M. I. Miga, K. D. Paulsen, F. E. Kennedy, P. J. Hoopes, A. Hartov, and D. W. Roberts. A 3D brain deformation model experiencing comparable surgical loads. Proceedings of the 19th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Chicago, IL, pp. 773-776, 1997. [PDF]

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Chapters

K. D. Paulsen, and M. I. Miga, "Chapter 15:  Biomechanical modeling for image registration:  Applications in image-guided neurosurgery",  Medical Image Registration, by editors:  J. V. Hajnal, D. L. G. Hill, and D. J. Hawkes, CRC Press, pp. 332- 362, 2001.

M. I. Miga, T. K. Sinha, and D. M. Cash "Techniques to Correct for Soft Tissue Deformations during Image-Guided Brain Surgery",  Biomechanics Applied to Computer Assisted Surgery, by editor: Yohan Payan, Research Signpost Publications, 2005.

M. I. Miga, M. M. Doyley, J. C. Bamber, John B. Weaver, K. D. Paulsen, and J. J. Ou, "Elastography in Breast Imaging", Emerging Technologies in Breast Imaging and Its Applications, by editor: Jasit Suri, American Scientific Publications, (in press), 2006.

A. L. Simpson, P. Dumpuri, W. R. Jarnagin, and M. I. Miga, 'Model-Assisted Image Guided Liver Surgery using Sparse Intra-operative Data', Soft Tissue Biomechanical Modeling for Computer Assisted Surgery, by editor: Yohan Payan, Springer Verlag, (in preparation), 2011.  

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